Nanotechnology for high precision cancer detection, delineation, and destruction
Moritz Kircher, PhD
Cancer represents one of the greatest health problems of modern society, and the incidence of many cancer types is still on the rise. Many novel approaches towards anti-cancer therapy have been devised and tested in the past decades, but only few have shown a real benefit for patients. If one would have to name three key elements in the approach to treating cancer, the terms early detection, precise delineation, and efficient tumor destruction would likely be cited. To this end, nanoparticles hold particular promise because multiple strategies and mechanisms can be combined into a single agent. Nanotechnology has already shown significant potential towards achieving these goals, however, there remain many challenges and hurdles. Novel ideas and principles are being developed in laboratories worldwide, but the complex path from the initial design, subsequent trial-and error, in vitro and in vivo validation in animal models to studies in humans is consuming tremendous effort and time. From this viewpoint, it is important that leading investigators share their knowledge with others so that cancer nanotheranostic approaches can be streamlined and accelerated. We therefore intend to highlight this topic in the special issue "Nanotechnology for high precision cancer detection, delineation, and destruction". We are highly interested in the following topics but not limited to:
- Nanoparticle approaches towards ultra-sensitive in vivo detection of cancer
- Nanoparticle approaches towards more precise delineation of cancer during interventional procedures
- Nanoparticle approaches towards highly effective tumor destruction
- Companion nanoparticle approaches towards more precise treatment efficacy prediction
- Device technology enabling and potentiating these goals
- Insights that further the clinical translation of anti-cancer nanoparticles
Both research articles and reviews will be considered. For more information on the journal and its style, please refer to “Instructions for Authors” at http://www.ntno.org/ms/author. All the invited and contributed manuscripts will undergo the standard peer-review procedure of the Journal “Nanotheranostics”, and will be scrutinized by the associate editor and at least two additional expert reviewers in the field. The manuscript submission DEADLINE is set for October 1st, 2016 and the first decision will conclude with 6 weeks from submission after peer-review process.
Manuscripts for this special issue should be submitted online at http://www.ntno.org/ms/submit (mark "Nanotechnology for high precision cancer Special Issue" in the "Suggested reviewers" field to identify the paper).
All inquiries should be sent to the guest editor(s) at the above email address.