CFP - Special Issue: Exploring the Frontier of Healthcare: Bioinspired and Biomimetic Nanotheranostics

Introduction

The rapidly advancing field of nano-biotechnology has opened new avenues for revolutionary applications in medicine and diagnostics. One of the most promising and innovative areas within this field is the development of bioinspired and biomimetic nanotheranostics. These nanotheranostics combine the principles of nanomedicine, nano-pharmacology, biomimicry, and theragnostic to create multifunctional nanoparticles that can simultaneously diagnose, treat, and monitor diseases. This editorial proposal aims to create a comprehensive platform for the dissemination of cutting-edge research, reviews, and discussions related to bioinspired and biomimetic nanotheranostics.

Rationale

Traditional approaches established for managing a targeted disease often face limitations of accuracy, specificity, and adverse effects. Bioinspired and biomimetic nanotheranostics capitalize on nature's ingenious designs to address these challenges in an acceptable manner. By mimicking biological systems, researchers can develop nanoscale structures capable of targeted drug delivery, real-time monitoring, and early disease detection. This proposal seeks to highlight the scientific advancements, challenges, and potential applications of this burgeoning field.

Applications

Bioinspired and biomimetic nanotheranostics have applications across various fields, including cancer treatment, cardiovascular disease, neurodegenerative disorders, and infectious diseases.

Scope

The proposed editorial project will cover a wide range of topics related to bioinspired and biomimetic nanotheranostics, including but not limited to:

Design and Synthesis: Exploration of various techniques and methodologies for designing and synthesizing efficient nanotheranostic agents inspired by natural structures and processes. An approach of green and sustainable biotechnology.
Biomimetic Approaches: Highlighting strategies that mimic biological systems, such as cell membranes, viruses, and bacteria, to enhance targeting, drug delivery, and imaging capabilities.
Therapeutic Modalities: To discuss the incorporation of therapeutic components, including chemotherapy agents, gene therapies, and photothermal/photodynamic therapies, into nanotheranostics for effective treatment strategies.
Imaging and Diagnosis: Exploring the integration of imaging agents, such as contrast agents, fluorescent dyes, and nanoparticles, for accurate and non-invasive disease diagnosis and monitoring.
Targeting and Specificity: Examining techniques to enhance nanoparticle targeting and specificity to diseased cells or tissues, reducing off-target effects and improving therapeutic outcomes.
Biocompatibility and Safety: Addressing the critical concerns of biocompatibility, immunogenicity, and long-term safety of bioinspired nanotheranostics for clinical translation.
Clinical Applications: Showcasing successful preclinical and clinical studies that highlight the potential of these advanced nanotheranostic platforms in real-world medical scenarios.
Ethical and Regulatory Considerations: Discussing the ethical implications and regulatory challenges associated with the development and deployment of bioinspired nanotheranostics.

Targeted Audience

The targeted audience for this editorial project includes researchers, clinicians, biomedical engineers, materials scientists, pharmacologists, and policymakers engaged in exploring nanotechnology, nanomedicine, and theranostics research for health wellness. It will also appeal to graduate students, postdoctoral fellows, and industry professionals interested in the latest developments in the field.

Conclusion

The proposed editorial project on "Bioinspired and Biomimetic Nanotheranostics" seeks to provide a comprehensive platform for the exchange of knowledge, covering the gaps, and ideas in this emerging and transformative field of high significance. By highlighting the potentials of state-of-the-art advanced nanotheranostic platforms, we aim to accelerate their translation from the laboratory to clinical applications, ultimately benefiting patients and advancing the field of personalized medicine.

Guest Editors

Murali M. Yallapu, PhD
Associate Professor | Department of Immunology and Microbiology
Core Codirector | Integraded Cancer Research Core
Program Coordinator & Member | TREC-South Texas Center of Excellence in Cancer Research
Coordinator | UTRGV-SOM DIM/STCECR Seminar Series
2.249 Biomedical Research Building
5300 North L Street
McAllen, TX 78504
Email:
Ph: 956-296-1734

Ajeet Kaushik, Ph.D.
Fellow: Indian Chemical Society
Assistant Professor of Chemistry
NanoBioTech Laboratory, Applied Research Center
Department of Environmental Engineering
Florida Polytechnic University, Lakeland, FL 33805-8531 USA
Email: ,

Google Scholar: https://scholar.google.com/citations?user=RYH8Z_4AAAAJ&hl=en

Kaushal Rege, PhD
Fulton Faculty Impact Professor
Director, Center for Biomaterials Innovation and Translation
Biodesign Institute
Arizona State University,
Tempe, AZ 85287-6106 USA
Email:

Arpan Pradhan, Ph.D.
Postdoctoral Research Fellow, Emory University, Atlanta, Georgia 30329, USA
Email:

Guest editors for manuscript handling

Anuradha Kumari, Ph.D.
Postdoctoral Fellow, Emory University, Atlanta, Georgia 30329, USA
Email:

Narendra Gupta, M.D., DMRD (Radiodiagnosis)
Head of the Department at Vasco healthcare pvt.ltd., Jaipur, Rajasthan, 302018, India
Head of the Department at Siddharth MR & CT Imaging
Email:

Manuscripts for the special issue can be submitted online at https://www.ntno.org/ms/submit (mark “Exploring the Frontier of Healthcare: Bioinspired and Biomimetic Nanotheranostics: Special Issue" in the "Suggested reviewers" field to identify the paper) between Sept, 01, 2023 to Sept, 02, 2024.

Detailed formatting instructions, in particular, the formatting of references, can be found in https://www.ntno.org/ms/author.

All inquiries should be sent to the guest editor at the above email address.

References

(1) Oroojalian, F.; Beygi, M.; Baradaran, B.; Mokhtarzadeh, A.; Shahbazi, M. A. Immune Cell Membrane-Coated Biomimetic Nanoparticles for Targeted Cancer Therapy. Small 2021, 17 (12), e2006484. DOI: 10.1002/smll.202006484 From NLM Medline.
(2) Niu, W.; Xiao, Q.; Wang, X.; Zhu, J.; Li, J.; Liang, X.; Peng, Y.; Wu, C.; Lu, R.; Pan, Y.; et al. A Biomimetic Drug Delivery System by Integrating Grapefruit Extracellular Vesicles and Doxorubicin-Loaded Heparin-Based Nanoparticles for Glioma Therapy. Nano Lett 2021, 21 (3), 1484-1492. DOI: 10.1021/acs.nanolett.0c04753 From NLM Medline.
(3) Krishnan, N.; Fang, R. H.; Zhang, L. Engineering of stimuli-responsive self-assembled biomimetic nanoparticles. Adv Drug Deliv Rev 2021, 179, 114006. DOI: 10.1016/j.addr.2021.114006 From NLM Medline.
(4) Chen, L.; Hong, W.; Ren, W.; Xu, T.; Qian, Z.; He, Z. Recent progress in targeted delivery vectors based on biomimetic nanoparticles. Signal Transduct Target Ther 2021, 6 (1), 225. DOI: 10.1038/s41392-021-00631-2 From NLM Medline.
(5) Zhou, J.; Kroll, A. V.; Holay, M.; Fang, R. H.; Zhang, L. Biomimetic Nanotechnology toward Personalized Vaccines. Adv Mater 2020, 32 (13), e1901255. DOI: 10.1002/adma.201901255 From NLM Medline.
(6) Zhao, P.; Wang, M.; Chen, M.; Chen, Z.; Peng, X.; Zhou, F.; Song, J.; Qu, J. Programming cell pyroptosis with biomimetic nanoparticles for solid tumor immunotherapy. Biomaterials 2020, 254, 120142. DOI: 10.1016/j.biomaterials.2020.120142 From NLM Medline.
(7) Chen, Z.; Zhao, P.; Luo, Z.; Zheng, M.; Tian, H.; Gong, P.; Gao, G.; Pan, H.; Liu, L.; Ma, A.; et al. Cancer Cell Membrane-Biomimetic Nanoparticles for Homologous-Targeting Dual-Modal Imaging and Photothermal Therapy. ACS Nano 2016, 10 (11), 10049-10057. DOI: 10.1021/acsnano.6b04695 From NLM Medline.