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Nanotheranostics, the sister journal of Theranostics, is a multidisciplinary and fully open access journal. Currently, the journal does not charge any publication or submission fees (Platinum open access). Nanotheranostics publishes innovative and original basic, translational and clinical research reflecting the fields of nanomedicine, nanoimaging, drug and gene delivery, nanoelectronic biosensors, and other areas. 

Regular features include high quality research articles, reviews or mini-reviews, rapid communication of preliminary data on innovative research, editorials, and letters to the editor. Educational articles on basic sciences, fundamental aspects and controversy related to pre-clinical and clinical studies or ethical issues of nanomedicine are also welcome. Timely reviews that provide updates on current applications and issues in nanomedicine and translational aspects of nanotheranostics and other topics are particularly welcome and will be given high priority.

Nanotheranostics employs a rigorous peer-review system, but also strives for rapid review turnaround times and is based on the same streamlined submission platform as Theranostics.

Recent Papers:


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Research Paper
A 2D nanotheranostic platform based on graphene oxide and phase-change materials for bimodal CT/MR imaging, NIR-activated drug release, and synergistic thermo-chemotherapy
Mehri Mirrahimi, Zahra Alamzadeh, Jaber Beik, Abolfazl Sarikhani, Mahdie Mousavi, Rasoul Irajirad, Tahereh Khani, Elnaz S. Davani, Ali Farashahi, Tahereh Shakerian Ardakani, Jeff W.M. Bulte, Habib Ghaznavi, Ali Shakeri-Zadeh
Nanotheranostics 2022; 6(4): 350-364. doi:10.7150/ntno.64790
[Abstract] [Full text] [PDF]


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Research Paper
Surface enhanced deep Raman detection of cancer tumour through 71 mm of heterogeneous tissue
Priyanka Dey, Alexandra Vaideanu, Sara Mosca, Marzieh Salimi, Benjamin Gardner, Francesca Palombo, Ijeoma Uchegbu, Jeremy Baumberg, Andreas Schatzlein, Pavel Matousek, Nick Stone
Nanotheranostics 2022; 6(3): 337-349. doi:10.7150/ntno.71510
[Abstract] [Full text] [PDF]


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Research Paper
EK-16A liposomes enhance HIV replication in ACH2 or J-Lat 10.6 cell engrafted NSG mice
Panpan Lu, Jinlong Yang, Xinyi Yang, Zhiming Liang, Jing Wang, Yanan Wang, Lin Zhao, Hanyu Pan, Xiaoting Shen, Yuqi Zhu, Jingna Xun, Hongzhou Lu, Huanzhang Zhu
Nanotheranostics 2022; 6(3): 325-336. doi:10.7150/ntno.69259
[Abstract] [Full text] [PDF]


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Research Paper
Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy
Flavia Rodrigues Oliveira Silva, Nelson Batista Lima, Maria Helena Bellini, Luiz Felipe Silva Teixeira, Eric Yiwei Du, Niloufar Jamshidi, Justin Gooding, Adam David Martin, Alexander Macmillan, Christopher Peter Marquis, Pall Thordarson
Nanotheranostics 2022; 6(3): 306-321. doi:10.7150/ntno.68789
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Review
Molecular Immune Targeted Imaging of Tumor Microenvironment
Taha Rakhshandehroo, Bryan Ronain Smith, Hannah J. Glockner, Mohammad Rashidian, Neeta Pandit-Taskar
Nanotheranostics 2022; 6(3): 286-305. doi:10.7150/ntno.66556
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Intracellular vesicle entrapment of nanobubble ultrasound contrast agents targeted to PSMA promotes prolonged enhancement and stability in vivo and in vitro
Reshani H. Perera, Eric Abenojar, Pinunta Nittayacharn, Xinning Wang, Gopal Ramamurthy, Pubudu Peiris, Ilya Bederman, James P. Basilion, Agata A. Exner
Nanotheranostics 2022; 6(3): 270-285. doi:10.7150/ntno.64735
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Visualizing surface marker expression and intratumoral heterogeneity with SERRS-NPs imaging
Lara K. Rotter, Naxhije Berisha, Hsiao-Ting Hsu, Kathleen H. Burns, Chrysafis Andreou, Moritz F. Kircher
Nanotheranostics 2022; 6(3): 256-269. doi:10.7150/ntno.67362
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Anti-PD-L1 F(ab) Conjugated PEG-PLGA Nanoparticle Enhances Immune Checkpoint Therapy
Christina K. Lee, Danielle F. Atibalentja, Lilian E. Yao, Jangho Park, Sibu Kuruvilla, Dean W. Felsher
Nanotheranostics 2022; 6(3): 243-255. doi:10.7150/ntno.65544
[Abstract] [Full text] [PDF] [PubMed] [PMC]

More ...

Editor-in-Chief:
Jonathan Lovell, PhD
Associate Professor, Biomedical Engineering
University at Buffalo, State University of New York
new Nanotheranostics is now indexed in the Web of Science, Biological Abstracts and BIOSIS Previews.

Nanotheranostics has been selected by The Literature Selection Technical Review Committee (LSTRC) for inclusion in MEDLINE, the prestigious index of U.S. National Library of Medicine.

Gold nanorods (GNRs) have attracted great interest for photo-mediated biomedicines due to their tunable and high optical absorption, high photothermal conversion efficiency and facile surface modifiability. GNRs that have efficient absorption in second near-infrared (NIR-II) window hold further promise in bio-applications due to low background signal from tissue and deep tissue penetration. However, bare GNRs readily undergo shape deformation (termed as 'melting effect') during the laser illumination losing their unique localized surface plasmon resonance (LSPR) properties, which subsequently leads....
'See what you treat and treat what you see, at a molecular level', could be the motto of theranostics. The concept implies diagnosis (imaging) and treatment of cells (usually cancer) using the same molecule, thus guaranteeing a targeted cytotoxic approach of the imaged tumor cells while sparing healthy tissues. As the brilliant late Sam Gambhir would say, the imaging agent acts like a 'molecular spy' and reveals where the tumoral cells are located and the extent of disease burden (diagnosis). For treatment, the same 'molecular spy' docks to the same tumor cells, this time delivering cytotoxic doses....
Cognitive impairment is a common aspect of multiple sclerosis (MS) for which there are no treatments. Reduced brain N-acetylaspartylglutamate (NAAG) levels are linked to impaired cognition in various neurological diseases, including MS. NAAG levels are regulated by glutamate carboxypeptidase II (GCPII), which hydrolyzes the neuropeptide to N-acetyl-aspartate and glutamate. GCPII activity is upregulated multifold in microglia following neuroinflammation. Although several GCPII inhibitors, such as 2-PMPA, elevate brain NAAG levels and restore cognitive function in preclinical studies when given at....
Rationale: To assess treatment effects of 4 complementary miRNAs (miRNA-100/miRNA-122/antimiRNA-10b/antimiRNA-21) encapsulated in a biodegradable PLGA-PEG nanoparticle, administered by an ultrasound-guided microbubble-mediated targeted delivery (UGMMTD) approach in mouse models of hepatocellular carcinoma (HCC). Methods: In vitro apoptotic index was measured in HepG2 and Hepa1-6 HCC cells treated with various combinations of the 4 miRNAs with doxorubicin. Three promising combinations were further tested in vivo by using UGMMTD. 63 HepG2 xenografts in mice were randomized into: group 1, miRNA-122/antimiRNA-10b/antimiRNA-21/US/doxorubicin;....
Congratulations to Dr. Chen for being elected as AIMBE fellow.